New Strategies Generate Optimism for Targeting "Undruggable" KRAS

New Strategies Generate Optimism for Targeting “Undruggable” KRAS

Vassiliki Papadimitrakopoulou, MD After 30 years of frustration, investigators are starting to make headway in their quest to develop therapies that counteract oncogenic mutations in the KRAS gene, a high-priority target in precision medicine that has long been deemed “undruggable.” 1-3 The discovery of binding pockets on a mutant […] Click here to view original[…]

Chinese AI assists with accurate cancer detection

GUANGZHOU, Oct. 10 (Xinhua) — Chinese researchers have developed an artificial intelligence (AI) medical tool that can help doctors improve diagnostic accuracy in detecting upper gastrointestinal cancers through analysis of imaging data from clinical examinations, according to an article recently published in the international journal Lancet Oncology. Upper gastrointestinal […] Click here to view original[…]

Targeting Patient Mindset as a Therapeutic Approach in the Setting of Cancer

Targeting Patient Mindset as a Therapeutic Approach in the Setting of Cancer

Cancer is a disease associated with negative psychosocial as well as physical effects. Researchers from Stanford University have put forward a “call to action” for the cancer community to focus on developing interventions that help patients with cancer develop more adaptive mindsets. This article was published in Trends in […] Click here to view original[…]

Experimental prostate cancer therapy delays disease in 'landmark' trial

Experimental prostate cancer therapy delays disease in ‘landmark’ trial

An experimental prostate cancer therapy may change the way patients are treated for the second-deadliest cancer in men. (CNN) — An experimental prostate cancer therapy may change the way patients are treated for the second-deadliest cancer in men. In a “landmark” phase III clinical trial, presented at the European […] Click here to view original[…]

Trio Wins Nobel Prize In Physiology Or Medicine For Work On Cells And Oxygen

Trio Wins Nobel Prize In Physiology Or Medicine For Work On Cells And Oxygen

The winners of the 2019 Nobel Prize in physiology or medicine are Gregg Semenza of the U.S., Peter Ratcliffe of Britain and William Kaelin of the U.S. They’re seen here on a screen during a news conference at the Karolinska Institute in Stockholm. Three scientists who made important discoveries […] Click here to view original[…]

Earlier Diagnosis and Treatment Are Next Steps in TNBC Paradigm

Earlier Diagnosis and Treatment Are Next Steps in TNBC Paradigm

Hope Rugo, MD There is an unprecedented array of therapeutic options for patients with triple-negative breast cancer (TNBC), with more approaches on the horizon. However, in the face of these promising investigational therapies, perhaps the most important issue in TNBC is that the focus must turn to diagnosis and […] Click here to view original[…]

Cancer patients who exercise have less heart damage from chemotherapy

Patients with cancer should receive a tailored exercise prescription to protect their heart, reports a paper published today in the European Journal of Preventive Cardiology , a journal of the European Society of Cardiology (ESC). “Cancer patients are often less active than adults without cancer,” said author Dr. Flavio […] Click here to view original[…]

Pink: A matter of survival: Advances in chemotherapy are making breast cancer treatable, not terminal

Pink: A matter of survival: Advances in chemotherapy are making breast cancer treatable, not terminal

[More Content Now] Hide caption Advancements in medicine and technology mean breast cancer patients are living longer, and many cancers are now treated as chronic illnesses rather than terminal diseases. Life expectancy, even for multiple stage 4 cancers, has risen. “It’s not a stretch to tell a woman newly […] Click here to view original[…]

FDA Recommends Use of Placebo Only in Certain Oncology Trials

Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Niraparib for the Treatment of Metastatic Castration-Resistant Prostate Cancer

RARITAN, N.J., Oct. 3, 2019 /PRNewswire/ — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for niraparib, an orally-administered poly ADP-ribose polymerase (PARP) inhibitor, for the treatment of patients with BRCA1/2 gene-mutated metastatic castration-resistant […] Click here to view original[…]

3 Drug Stocks Poised for Gains After Cancer Conference

3 Drug Stocks Poised for Gains After Cancer Conference

Drug and biotechnology stocks that offer a range of cancer therapies have come under the microscope this week after a five-day conference, put on by the European Society for Medical Oncology, concluded Tuesday. The Barcelona-based event provided an opportunity for leading companies in the space to present new findings […] Click here to view original[…]

Cancer Drug Combos Causing Cost Effectiveness Headaches

Cancer Drug Combos Causing Cost Effectiveness Headaches

Barcelona — The increasing use of drug combinations in oncology will lead to greater uncertainty over cost-effectiveness, argue leading experts, with patients potentially left unable to access combination therapies that offer improved outcomes but at inflated cost to the health service. Carla Deakin, programme director, Commercial & Managed Access […] Click here to view original[…]